Key CBD Oil Benefits and Use Cases
Cannabidiol is a widely used natural therapy for a variety of ailments. Cannabidiol, or CBD, is a chemical component of the cannabis plant known as Cannabis sativa (1Trusted Source). It’s one of over 100 compounds called cannabinoids found in the plant.
Tetrahydrocannabinol (THC) is the most psychoactive cannabinoid found in cannabis, and it generates the “high” sensation that is commonly associated with marijuana. CBD, on the other hand, is non-psychoactive.
Because of its purity, cannabidiol has been dubbed “nature’s chemical wonder.” It may be used to treat a variety of afflictions without the psychoactive or mind-altering effects associated with marijuana or certain pharmaceutical medications.
CBD oil is made by extracting CBD from cannabis plants, then diluting it with a carrier oil like coconut or hemp seed oil.
With more and more people turning to cannabis for pain relief, it’s gaining ground in the health and wellness sector, with some scientific research suggesting it may help with chronic pain and anxiety.
Here are seven health advantages of CBD oil that have been scientifically proven.
Legality of CBD
Despite the fact that the legal status of CBD is uncertain, it may be purchased in most parts of the United States. CBD has been legalized in every state [5] with varying degrees of restriction, so while the federal government continues to regard cannabidiol as a drug, it cannot constantly enforce it.
However, there are still many people who obtain CBD from online platforms that have a medical cannabis license. The status of CBD is expected to alter as a result of the present bipartisan consensus in Congress to legalize hemp crops.
However, the government’s position on CBD is dependent in part on whether it originates from marijuana or hemp. The real question now is: what are the advantages of CBD? We look at what CBD has to offer and which health problems and conditions may be treated with it.
The Advantages of Long-Term Treatment
Can Relieve Pain
Pain is a part of our lives, whether acute or chronic. The GSK Global Pain Index 2017 found that 95 percent of the world’s population had experienced bodily pain at some time, while 86% of people have experienced head discomfort.
CBD has been discussed by those who have experienced any sort of discomfort. Cannabidiol is thought to offer possible therapeutic advantages, such as pain alleviation, and people are interested in it.
CBN binds to a wide range of proteins in the central nervous system and body, including components of the endocannabinoid system (ECS), such as CB1 receptors in the brain and spinal cord, as well as CB2 cannabinoid receptors present in the immune system and spleen.
THC has an affinity for CB1 receptors, while CBD has an inverse influence. CBD inhibits the absorption of a natural cannabinoid molecule called anandamide (an endocannabinoid). The increased levels in the circulation aid to reduce pain throughout the body when anandamide signaling is stimulated by CBD.
CBD activates the body’s natural pain-killing mechanism, which is to use receptors that respond to glycine. The study discovered that CBD tends to target alpha-3 glycine receptors in order to reduce inflammation and combat chronic pain, which is linked with malfunctioning glycine receptors and the ability to respond to pain sensation in the spine.
CBD has been shown to have anti-inflammatory, anti-seizure, and pain killing effects. CBD acts through the TRPV1 receptor, which is a type of nerve receptor that responds to specific types of temperatures and chemicals, according to a 2014 study in the British Journal of Pharmacology.
Another study published in the Journal Neurotoxicology revealed that CBD lowers glutamate levels in the spinal cord and brain, according to the September 2015 edition of this journal. Glutamate is linked with pain transmission and increased pain sensitivity.
CBD continues to be shown in studies to help with a wide range of pain-related issues. In a 2016 animal research published in the European Journal of Pain, various dosages of transdermal CBD gel (6.2 mg and 62.3 mg given to laboratory rats) were found to be successful in reducing arthritis discomfort and inflammation.
Several studies have arrived at the same conclusion. In 2017, The Journal of Pain published a study that demonstrated that nerve damage and joint pain in rats with osteoarthritis might be prevented.
Summary: CBD has been found to be effective in the treatment of chronic pain, according to academic research.
Potential for the treatment of fibromyalgia
Sir William Gowers first described fibrositis, which is now known as fibromyalgia, in 1879. It is a condition characterized by soft tissue pain that migrates throughout the body and is exacerbated by overuse of tissues. Trigger points are painful nodules that can be found in the neck and shoulder, which are generally severe to enough to prevent physical activity. It also has a link with anxiety and depression.
Women with fibromyalgia frequently suffer from both migraines and sleeplessness. This condition is the most prevalent diagnosis in American rheumatology clinics. The authors observed that this condition, like migraines, might be linked to secondary hyperalgesia (a lowered pain threshold in primarily affected regions).
According to the researchers, CBD treatments might help with pain. Some of the several symptoms that can be treated with cannabinoids have already been addressed by fibromyalgia patients. In an uncontrolled trial involving nine people, dosages of 2.5 – 15 mg THC daily for three months were given.
The ethics committee, however, did not allow the placebo used in this research. As a result, only four patients remained in the study after THC toxicity forced the rest of them to depart early. Subjective pain was reduced among those who completed the study.
A study was conducted comparing the effectiveness of pharmaceutical drugs approved by a regulatory body to CBD in treating fibromyalgia. The prescription medicines were less effective than CBD.
Summary: CBD is a form of cannabis that has been demonstrated in studies to help people who suffer from fibromyalgia.
CBD for Irritable Bowel Syndrome
IBS, also known as spastic colon, is a condition marked by GI (gastrointestinal) discomfort, spasm, and altered bowel actions that can be either mostly constipation or diarrhea, or they may switch from one to the other.
The most common symptom of IBS is abdominal cramps, which are often accompanied by pain or a sensation of fullness. The attacks can be brought on by dietary mistakes such as overeating or particular meals, and they’re highly linked to anxiety. If gastrointestinal infections like as antibiotics or food poisoning are strong enough, the episodes may continue but only for a short period of time.
The ECS has an impact on intestinal GIT function, propulsion, and inflammation in people. This makes it reasonable that CBD may be used to treat IBS symptoms. Unfortunately, at the same time, many patient testimonies have shown that CBD can help with IBS symptoms, while there is a lot of anecdotal evidence on the internet. CBD has yet to be studied extensively in trials. There isn’t a lot of clinical research indicating that it can help with IBS problems. The modulation of the gut ECS, on the other hand, may provide a useful therapeutic target for IBS.
Summary: Partially Effective – According to academic research, CBD can aid with Irritable Bowel Syndrome.
May Help With Multiple Sclerosis
Multiple Sclerosis is an autoimmune disease in which the immune system eats and destroys the protective sheaths covering nerves in the body. There is no cure for Multiple Sclerosis, which is a chronic, autoimmune illness.
Treatment for MS is primarily focused on reducing pain and slowing disease progression. One of the most prevalent symptoms is muscular spasms, which can be severe enough in some persons to cause constant discomfort.
According to a study, CBD’s short duration of usage might help reduce spasticity in persons suffering from multiple sclerosis. The results were inconclusive. Many patients claimed that their problems had improved. Nonetheless, further research is needed to demonstrate CBD’s efficacy in treating MS.
Summary: CBD is extremely effective against a lot of illnesses. Academic study confirms that CBD can be used to fight multiple sclerosis.
The ability to reduce inflammation
CBD, according to a study published in the Journal of Experimental Medicine, can significantly reduce chronic inflammation and pain in rats and mice. According to the poll, non-psychoactive components in CBD may help to decrease inflammation.
CBD’s anti-inflammatory properties are attributable to its interactions with the Endocannabinoid system, which is present in nearly all organs throughout the body. Because inflammation is reduced systematically as Cannabinoids interact with the Endocannabinoid system found in most organs across the body, CBD has an anti-inflammatory effect. The therapeutical potential of CBD is wide-ranging, since it inhibits inflammation.
Chronic inflammation, according to the National Center for Biotechnology Information, has been linked to a range of non-infectious diseases including cancer, heart disease, Type 2 Diabetes, Alzheimer’s disease, and even autoimmune disorders. CBD has been found in studies to help lower inflammation and alleviate some of these illnesses.
Summary: Not very Effective – According to academic research, CBD can assist with multiple sclerosis.
Lowered blood pressure
In a research to examine whether CBD lowers blood pressure in humans, nine healthy male participants were given 600 mg of CBD in a randomized, placebo-controlled crossover study. The cardiovascular variables were measured with a laser Doppler and finometer.
CBD reduced blood pressure in both healthy individuals and those who were stressed, increased heart rate, and decreased stroke volume. Cold stress caused blood pressure to drop and the heart rate to rise less in people who received CBD than in those who did not receive it.
CBD has been proved to reduce resting blood pressure and the blood pressure response to stress, especially in instances of cold stress.
Summary: Cannabidiol is an ingredient in cannabis that has shown to be therapeutic in rats with high blood pressure. CBD can help with lower blood pressure, according to academic research.
Potentially May Relieve Cancer-Related Symptoms
Aside from cancer, people who are suffering from this disease must also endure with distressing symptoms such as sadness, pain, and sleeplessness. Furthermore, treatment is frequently followed by chemotherapy-induced vomiting and nausea. Fortunately, CBD alleviates cancer symptoms.
Some cancer patients find it difficult to respond to traditional pain medications such as opioids, and those who do may become dependent on them.
According to research, CBD offers a different sort of therapy that is more efficient and non-habit-forming. According to this research, CBD can help relieve pain 30% more effectively than THC alone or common medication.
Vomiting and nausea are the most prevalent and abhorred symptoms of chemotherapy. They can be so powerful that up to 25% to 50% of cancer patients will refuse or postpone treatment. CBD may significantly reduce or eliminate these symptoms.
Researchers gave a daily CBD spray or placebo to cancer patients after chemotherapy in another study. Those who were given the CBD spray had a 49 percent reduction in nausea and vomiting-related problems, according to one research.
There’s a growing body of evidence to suggest that CBD might aid slow the spread of aggressive cancer cells[26] and even help cancer cells die. However, there is still a lot to learn.
Summary: No negative side effects have been reported.
Anti-Tumor Effects
Cannabinoids, like CBD, have been researched to see if they can help reduce cancer-related symptoms and whether CBD can also prevent tumors from developing.
A 2012 study compared animals that were given carcinogens in the lab and subsequently treated with CBD, and it revealed that they had a decreased risk of colon cancer. THC has been shown in several studies to aid in the reduction or prevention of tumors. In a 1996 research, CBD was proven to lower the incidence of both hepatic adenoma and benign tumours in animal models.
In 2015, California’s medical records of 34,000 people were evaluated. As a consequence, those who used cannabis rather than cigarettes had a 45 percent lower probability of bladder cancer than the general population. CBD’s effect on cancer is still being researched, with additional study needed to discover how it aids in cancer prevention and cure.
Summary: CBD is legal in the United States and has been found to have anti-tumor effects in academic research.
Treats Skin Conditions
Following the legalization of marijuana for medical and recreational reasons, the skincare industry has incorporated CBD-infused topical treatments. According to a survey conducted by Sky Bet, 36% of CBD product users claim that it has aided in treating a variety of health issues.
Fortunately, the same way CBD oil has shown excellent effects on the inside of the body; it also works for skin. People have started using CBD oil skin products because of their effectiveness in reducinginflammations and acne breakouts.
CBD is an anti-inflammatory cannabinoid that can help with skin problems like psoriasis and eczema. CBD has anti-inflammatory properties, just like other skin treatments for ailments such as psoriasis and eczema. CBD oil’s strong antioxidant qualities aid in the speeding up of the healing process.
Summary: CBD is a powerful antioxidant and neuroprotectant. It’s also been shown to help cure skin issues in scientific studies.
Protects and Heals the Skin
Our skin has the greatest concentration and amount of CB2 receptors of any other organ in the body. CBD oil is effective against a variety of skin problems, according to several studies [33] such as acne and eczema, by promoting abnormal cell death.
CBD is a powerful antioxidant, which means it may help the skin by repairing damage caused by free radicals such as environmental pollutants and UV rays when applied as a serum, lotion, salve, or oil.
The skin contains cannabinoid receptors, which assist control sebum production in the sebaceous glands. As a result, pharmaceutical firms are developing cannabis-based topical treatments for various ailments such as psoriasis and acne, as well as aiding in the regeneration of damaged skin.
There are historical papers that demonstrate that cannabis medicines have been used to cure wounds in both animals and people from all across the world for hundreds of years. The use of CBD oil and concentrated cannabis to treat skin disorders and skin cancer is becoming more popular by the day.
Several individuals who utilized CBD and THC topical treatments have been recorded to have survived melanoma and skin cancer. Rick Simpson is a good example, as he used cannabis oil to treat basal cell carcinoma with success. He now distributes a line of CBD goods under the name “Living Tree Organics.”
Summary: CBD has been found to protect and heal the skin in scientific studies.
May Reduce Acne
Acne is a significant health concern affecting more than 9% of the population. Acne occurs when dead skin cells, extra oil, or soil build up in the pores and block them. Propionibacteria acnes, or P.acnes, bacteria that live in hair follicles when the skin pores are blocked become active and inflame acne.
Bacteria accumulate on the skin, causing red pimples. To keep the germs at bay, maintain your skin clean and use a skin oil that won’t clog it. CBD oil has been shown in studies to have acne-fighting properties. It also has anti-inflammatory effects and aids in the prevention of sebum production.
CBD oil inhibits the growth of Propionibacterium acnes, which is an acne-causing bacteria. CBD oil works by targeting cells that promote acne. Unlike topical treatments and pharmaceutical medications, CBD oil targets disease-causing cells in individuals with acne-prone skin types. As a result, CBD promotes skin healing without causing irritation or dryness.
However, in order to cure acne, you must avoid stressing out during the healing process since it is a natural occurrence. While utilizing CBD for acne, you may also incorporate CBD for anxiety into your treatment to help you relax and allow your entire skin to heal. To assist CBD’s impact, add a few drops of CBD in your beverage or meal.
Summary: CBD is a novel cannabinoid found in cannabis plants. According to academic research, it can help reduce acne.
Treat Lupus
Lupus is a chronic disease that has no cure. As a result, drug firms have been attempting to develop more effective treatments for lupus. Lupus, whether treated or not, causes the patient massive amounts of discomfort.
However, with the present opioid addiction and overdose epidemic, a lot of pressure is placed on law enforcement and the medical community. Fortunately, there is a wealth of study demonstrating that CBD oil aids in pain and inflammation relief , in which case Lupus entails significant inflammation.
CBD also seems to have an anti-inflammatory effect. According to a study published in Cellular Immunology in 2018, CBD may change T-cells, which are components of the immune system, after spinal cord injury [43]. It is thought that T-cell malfunctions are involved in Lupus.
Furthermore, pain can be caused by neuropathy or nerve damage. CBD oil has been found in studies to help relieve HIV, diabetes, and other types of pain.
Summary: CBD is a type of cannabis that has been used for medicinal purposes since ancient times. CBD products are gaining popularity as many studies have shown they can benefit lupus patients in a variety of ways.
Potentially May Help Heart Health
Heart disease is an increasingly common illness throughout the world. It is one of the most prevalent causes of death in the United States. People have begun to prioritize a healthy lifestyle and diet, which CBD oil may aid.
CBD oil is showing promise in the treatment of anxiety. According to a study published by CBN CBD Science in January 2019. CBD could help prevent stress-induced blood-pressure fluctuations. CBD’s ability to lower high blood pressure has also been reported in recent research, as well as its potential for heart and circulatory benefits.
Men were subjected to stressful tests that typically elevate blood pressure in a research. CBD, on the other hand, produced them feel lesser blood pressure rises than usual during stress testing.
Furthermore, studies conducted in animals have shown that CBD can help reduce cell death and inflammation caused by heart disease due to its strong stress-reducing and antioxidant qualities.
Summary: Effective – According to academic study, CBD may be beneficial for cardiac health.
Better Cholesterol Profiles
According to a 2013 study, 4,652 people were utilized to investigate the impact of cannabis on their metabolic systems. They compared non-users to former and current users. Current cannabis users had greater blood levels of good cholesterol, known as high-density lipoprotein (HDL-C), according To their findings, current cannabis consumers had higher blood levels of high density lipoprotein (HDL) than non-users.
In 2016, researchers at St. Joseph’s Hospital in Hamilton, Ontario compared the levels of good cholesterol (HDL) and bad cholesterol (LDL-C) in 700 Inuit individuals who used cannabis recreationally with those who didn’t use it regularly.
Summary: CBD has been shown to have a beneficial impact on cholesterol levels in studies.
Lowered Risk of Cardiovascular Disease
Atherosclerosis affects both developed and developing nations, particularly those in the Western world. This persistent inflammatory condition has been linked to diet and lifestyle. It includes the progressive accumulation of immune cells that transport oxidized LDL, or atherosclerotic plaques.
It is an involuntary, protective movement made by the body in response to damage in the wall lining of arteries caused by infectious germs, high blood pressure, or an abundance of homocysteines. It’s been shown that inflammatory chemicals can activate a cycle that leads to atherosclerotic plaque growth.
In a study from 2005, low-doses of cannabis extract slowed the progression of atherosclerosis in animals. It was later claimed that there was a lot of therapeutic potential for diseases such as atherosclerosis. CBD had cardio-protective effects in a 2011 research involving heart attacks.
Summary: Effective – According to academic study, CBD reduces the risk of heart disease.
Helps with Bone Diseases and Bone Fractures
The rate at which old bone material is replaced by new bones varies between 10% and 20% each year (bone metabolism). Cannabinoids assist with this important aspect of maintaining strong, healthy bones over time.
Cannabidiol (CBD) oil can help protect against age-related bone diseases like osteoarthritis and osteoporosis by inhibiting an enzyme that destroys the body’s bone-building chemicals. The body does not create new bone and cartilage cells in these situations.
CBD oil promotes the healing of bones, which encourages new bone-cell formation and lowers the risk of bone resplinture due to a stronger fracture callus.
Summary: Effective – Some academic research suggests CBD can prevent bone disease and fractures.
Reduces the risk of diabetes
Researchers discovered that current cannabis users had fasting insulin levels up to 26% lower than non-users. They also had higher HDL cholesterol levels, which protect against diabetes, and 17% reduced insulin resistance levels.
Users that had previously used cannabis but are now without similar outcomes, however with fewer connections. This implies that cannabis’ protective effect fades over time.
Because diabetes is an inflammatory disease, CBD can assist thanks to its anti-inflammatory qualities. CBD has shown promise in lowering blood sugar levels in people with type 2 diabetes who don’t take insulin and improve insulin sensitivity.
CBD was studied in the Journal of Clinical Hemorheology and Microcirculation in 2016, which found that it has an anti-inflammatory effect on the pancreas [55]. CBD’s potential to delay and prevent Type 1 Diabetes development was reported in Lisbon, Portugal, in 2016.
The interaction between insulin management and cannabinoids may aid in the prevention of obesity and type 2 diabetes in the future, since excess insulin promotes sugar conversion into stored fat, resulting in weight gain and obesity.
Summary: Partial Effectiveness – According to certain academic research, CBD may help lower the incidence of diabetes.
Potentially Reduces Risk of Obesity
Cannabis users have a smaller waist circumference, a lower body mass index, and a reduced risk of obesity, according to several research. In 2011, an investigation was conducted among over 52000 people in the American Journal of Epidemiology that revealed that cannabis users had about 1/3 fewer chances of being obese.
Despite the fact that cannabis users eat more calories on a daily basis as a result of THC’s stimulation of ghrelin, they nevertheless consumed fewer fats and carbohydrates. Ghrelin boosts your hunger as well as your carbohydrate metabolism.
CBD reduced diabetes in lab rats by itself, according to research published in 2006. CBD can help you lose weight by encouraging your body to convert white fat into brown fat, which promotes normal insulin production and sugar metabolism.
Summary: Approximately 50% Effective – CBD has been shown in some academic research to help decrease the incidence of obesity.
Helps support brain health
Cannabinoids are neuroprotective, which means they aid in the maintenance and functioning of the brain. The effect is caused by cannabinoids’ actions on the brain, such as enhanced mitochondrial function and damaged cell removal.
Cannabidiol (CBD) and some of the antioxidant chemicals found in cannabis can also help protect glutamate against toxicity. Extra glutamate activates nerve cells in the brain, causing them to fire, resulting in over-stimulated cells, which might result in cell damage or death.
Cannabinoids preserve the brain’s health and function by shielding it from damage. CBD has an anti-inflammatory impact on the brain as well.
Summary: There is no proof that CBD has neuroprotective qualities.
Might Have Neuroprotective Properties
Hemp oil derived from cannabis sativa has been shown to have neuroprotective effects, which help to protect the brain from damage. CBD also promotes the growth and development of new neurons by inhibiting cell death and stimulating regeneration. Traumatic blows, ischemia, or genetic and autoimmune disease might result in long-term or temporary brain damage.
CBD has been shown in studies to protect the brain from this damage and help recovery. This implies that CBD can be used as a therapeutic tool for those who have suffered a traumatic brain injury, spinal cord disease, spinal cord injury, epilepsy, or stroke.
CBD can also help protect against further damage to the brain caused by these diseases, which are known as neurodegenerative disorders. CBD has been shown to be neuroprotective in cell and animal studies, suggesting that it may help prevent neuron damage. A 2017 study published in The Journal of Epilepsy Research found that CBD had anticonvulsant effects.
Summary: CBD is not only effective, but it has neuroprotective effects that are supported by academic research.
Create Resilience to Trauma and Degeneration
The production of new cells in our brain, called neurons, gradually slows as we get older. The news cells should be constantly produced to maintain brain health and avoid neurodegenerative disorders.
According to a research published in 2008, even in the brain of an elderly animal, small amounts of THC- and CBD-like cannabinoids promoted the development of new nerve cells. CBD also aids in the prevention of neuropathy and other nerve-related illnesses. [62]
CBD’s anti-inflammatory effect makes it useful in treating a wide range of illnesses, including arthritis. CBD’s ability to block the lipoxygenase enzyme means that it may help prevent or cure neurodegenerative diseases by reducing inflammation. This suggests that CBD might play a role in whether or not you get sick with the disease you’re predisposed to. As a result, CBD may be utilized to avoid or treat various types of brain disease in the future by decreasing inflammation.
Summary: There is no scientific evidence to show that CBD can help you avoid stress and distress or preserve your brain health.
Relieve Nerve Pain
Nerve pain is caused by malfunctioning, irritated, or damaged nerves. The nerve will send conflicting signals to the brain and other body systems when confused and damaged. Pain sensitivity varies from person to person.
A clinical trial published in Neurotherapeutics, for example, found that patients with neuropathy could profit from cannabinoid therapy. CBD inhibits neuropathic and inflammatory pain by targeting a3 glycine receptors, according to the Journal of Experimental Medicine.
However, the mechanism by which CBD inhibits or alleviates pain is still unknown. CBD’s intoxicating effects may divert users from their discomfort and help them alleviate it for a brief time.
Summary: Effective – According to academic research, CBD can help relieve nerve pain.
Potential antioxidant
CBD has been shown to have antioxidant effects, which may help protect against oxidative stress, a condition in which the body has too many free radicals and antioxidants are unable to neutralize them. As a result of rising environmental toxicity, it is a relatively recent problem.
Since 2001, the US government has recognized the antioxidant benefits of cannabis treatment for neurodegenerative diseases like Parkinson’s disease, Alzheimer’s disease, dementia, and HIV since these illnesses are linked to free radicals and when the body’s cellular structure fails.
CBD oil has neuroprotective and antioxidant properties that help to alleviate brain damage caused by free radicals, according to two separate research.
Summary: Partly Effective – CBD has been shown to have antioxidant effects in academic research.
Benefits of psychotic treatment
May relieve anxiety and depression
Anxiety affects 18% of the population in the United States every year, according to the Anxiety and Depression Association of America. According to Mental Health America, 6% of people suffer from depression on an annual basis in the United States.
Doctors typically advise people with chronic anxiety to avoid marijuana since THC might cause paranoia or exacerbate symptoms. CBD, on the other hand, can help with both anxiety and depression if the THC level is kept at 0.03%.
CBD is a non-psychoactive chemical that may help people cope with various anxiety-related behavior problems, including general anxiety disorder, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), social anxiety disorder, panic attack, and substance abuse disorders, according to a study published in 2015 in the Neurotherapeutics journal.
However, there is no human study; these findings were derived through clinical trials, laboratory research, and epidemiological studies.
CBD has also been found to aid in the treatment of depression. CBD improves both serotonergic and glutamatergic signaling in depressed persons, which are deficient. CBD oil has shown promise in studies looking at how it can be used to treat depression.
Summary: Effective – CBD can help alleviate anxiety and sadness, according to academic study.
May Help Reduce Fear Reaction or Effects
Humans are thought to have two natural fears: the fear of loud noises and the fear of falling. Fear of dogs, snakes, spiders, heights, being alone, clowns…numerous other phobias people endure.
Fear-related disorders, such as post traumatic stress disorder (PTSD) and panic attacks, are marked in the DSM-5. According to a report published by the British Pharmacological Society in 2017, numerous experiments proved that CBD helps decrease acquired fear reaction in people with PTSD and phobias.
CBD helps eliminate fear by disrupting memory reconsolidation, acutely decreasing fear expression, and enhancing fear extinction, according to one study. As a result, CBD can help you overcome the effects of fear, whether it’s post-traumatic stress disorder (PTSD), phobias, or other life-changing experiences that cause trauma.
Summary: Effective – CBD has been shown in studies to help reduce anxiety and fear reactions.
May Reduce Stress
Stress and anxiety can have a negative influence on your mental, social, and physical health. A number of scientific studies show that CBD may help reduce stress as part of a treatment plan.
CBD has been proved to relieve anxiety in a study on 32 different rodents, with only one rodent failing to show positive results. Test rats are put into stressful circumstances and their anxiety and stress levels are evaluated in these tests.
CBD may help with a variety of anxiety and stress-related issues, according to a 2015 study. CBD was found to aid in the treatment of disorders such as SAD, panic disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder, and obsessive-compulsive disorder (OCD).
Summary: Effective – CBD has been studied by academics and shown to help reduce stress.
May help with insomnia
Up to 60 million people in the United States suffer from insomnia or suffer from both acute and chronic sleep difficulties. Insomnia can have a significant impact on a person’s life, and when it becomes persistent, it may be tough to cure.
Prescriptions for sleeping pills and sleep disorders can lead to addiction and severe side effects. CBD oil has been found in studies to aid reduce the symptoms and severity of insomnia for a month after beginning therapy. However, the outcomes varied over time.
Summary: Partly Effective – CBD may help you sleep better, according to certain academic research.
CBD May Fight Addiction
According to a Substance Abuse review published in 2015, CBD can assist individuals battling drug addictions in overcoming withdrawal symptoms. They found that CBD has the potential to help people recovering from cocaine, opioid, and psychostimulant addiction.
They also discovered that it has the potential to assist treat tobacco and cannabis addiction. CBD has been shown in studies to reduce or even block THC’s impact on the brain.
CBD, according to a review published in Neurotherapeutics, helps with the treatment of substance abuse-related symptoms such as mood disorders, anxiety, sleeplessness, and pain.
Summary: Partly Effective – CBD has been shown in studies to be beneficial for addiction treatment.
Reducing cigarette addiction
According to a study published in Addictive Behaviors, smokers who used CBD vape pens or inhalers reduced their smoking quantity without experiencing nicotine withdrawal symptoms.
In a 2013 study, researchers tested the effects of inhaled CBD on 24 cigarette smokers who sought to quit smoking for a week. Twelve of the participants who received CBD reduced their smoking by around 40%, whereas the group that received a placebo showed no change in the number of cigarettes they smoked.
CBD oil has been shown to help with a wide range of ailments, including anxiety and stress. Since most smokers are compelled to smoke in reaction to stressful events, CBD oil can assist with worry and tension.
Summary: Effective – CBD has been shown in academic studies to reduce smoking activity.
May help with drug (opioid) quitting and addiction
The majority of opioids are used to treat pain and mood disorders. CBD helps people suffering from discomfort, such as chronic pain, anxiety, or depression, by providing relief for their symptoms. As a result, CBD has been proved to lower opioid cravings and reduce anxiety.
It accomplishes this without raising the risk of addiction, causing any negative effects, or producing a high. CBD will function as a natural non-addictive, non-psychoactive cure for opioid withdrawal and aid in preventing relapse.
Because of this, CBD may help people who are already suffering from opioid addiction by alleviating cravings and withdrawal symptoms.
Summary: CBD is only partially effective. CBD has been found to help with drug (opioid) withdrawal and addiction in some academic research.
CBD is an effective remedy for heroin addiction
CBD has been found to help reduce heroin cravings in a 2017 Trends in Neuroscience study.
CBD has been observed in several research to have specific interaction with dopamine and serotonin receptors in the brain. These receptors are damaged by excessive heroin and opioid use, limiting your brain’s capacity to comprehend mental, physical, and emotional events correctly.
Summary: No Proof – CBD, on the other hand, has not received significant scientific study to show that it can help heroin addiction.
CBD May Improve Mood and Relieve Stress
CBD has been found to act on several pathways in the brain, altering the activity of important mood regulating chemicals such as norepinephrine and serotonin, according to a 2018 research. 5HT1A is a serotonin receptor that affects anxiety, hunger, sleep, and addiction.
CBD activates the serotonin 5-HT1A receptor in a manner similar to that of serotonin, producing the same effects. As a result, CBD may help to increase serotonin levels in the brain, resulting in feelings of calmness and euphoria.
CBD also acts as a positive modulator for GABA, an inhibitory neurotransmitter that dampens the effects of excitatory chemicals like cortisol and norepinephrine, resulting in a relaxing effect. In the brain, CBD promotes the expression and creation of GABA.
CBD has been proven to promote the formation of mood-boosting neurotransmitters in humans, such as serotonin. People with gloomy feelings can profit from it.
Summary: Effective – CBD may help reduce anxiety, according to academic studies.
Inner tranquility
CBD has shown promise in the treatment of a number of skin issues. One’s Endocannabinoid system is believed to be crucial to one’s skin health. CBD has been found to aid in the reduction of oil and acid production, which can lead to acne.
Other research has shown that phytocannabinoids have topical anti-inflammatory effects. CBD oil was found to have an anti-inflammatory effect on sebaceous glands and to help reduce skin oil production, which leads to acne in test tube studies.
CBD’s ability to reduce inflammation and control sebaceous glands makes it an excellent topical agent for soothing the skin from the inside out.
Summary: No proof – There is currently no academic evidence to support the claim.
Achieve Clarity Not a High
Despite the fact that CBD is derived from cannabis, it does not appear to have psychotropic or psychoactive effects. CBD, on the other hand, only contains traces of THC, which has a mind-altering effect.
Although CBD and THC have nearly the same composition, they have a variation in structure that gives each substance distinct medicinal qualities. CBD has a hydroxyl group, whereas THC has a cyclic ring that induces intoxication. CBD, on the other hand, does not have an equivalent property. As a result of this, CBD can counteract the influence of THC by reducing anxiety and tension, giving you clarity instead of euphoria.
Summary: No Proof – CBD oil has not been proved to be more effective than other CBD products. However, there isn’t enough academic research to demonstrate that CBD gives clarity rather than intoxication.
Increased Effectiveness
Depression, anxiety, and other mood problems are common. Many individuals suffer from depression, anxiety, or other mood issues that render them ineffective in their daily lives. The quality of many people’s lives has been ruined by mental issues.
Fortunately, several medical experts have discovered that CBD reduces symptoms of mental illness such as depression and anxiety. CBD can also help with pain relief, making one’s life less productive. CBD may also help to relieve neuropathic pain caused by multiple sclerosis and arthritis-induced physical agony. People who suffer from inflammatory disorders that cause discomfort may benefit from using CBD oil to alleviate their suffering.
Summary: No Proof – CBD does not appear to improve the efficacy of endocannabinoids, according to scientific research.
Alzheimer’s Disease Help
CBD has been shown in studies to be beneficial in the treatment of Alzheimer’s disease, similar to how it may help people with pain, inflammation, multiple sclerosis, chronic discomfort, and cognitive impairment. A recent study that focused on using CBD to treat Alzheimer’s found that CBD has neuroprotective properties that may help cure diseases affecting the nervous system such as Alzheimer’s.
CBD’s effectiveness in this regard is due to its capacity to preserve nerve cells from degenerating and being damaged, as well as its antioxidant qualities. CBD has also been shown to have anti-Alzheimer’s effects in mice, according to the same study. CBD was found to be able to significantly reduce harmful side effects in Alzheimer’s patients and enhance their cognitive function. While there is no direct evidence of this, CBD may hold the key to helping Alzheimer’s patients and slowing down its progression.
Summary: Effective – CBD can assist people with Alzheimer’s disease. According to academic study, CBD can help patients heal faster.
Antipsychotic Effects
Antipsychotics block the actions of neurotransmitters in the brain, such as acetylcholine, noradrenaline, serotonin, and dopamine. Dopamine overproduction is caused by excessive dopamine levels, and antipsychotic drugs target dopamine receptors to reduce dopamine synthesis.
CBD may help to normalize changes in the brain regions linked to psychosis development, according to a study published in February 2019. CBD improves cognitive function and patients’ quality of life as well as their global functioning as a result of their illness.
CBD has been proved to help reduce psychotic symptoms in individuals who suffer from mental illnesses such as psychosis and schizophrenia. People with these disorders have reported improved after taking CBD, although the findings haven’t been verified for all mental illnesses.
Summary: Effective – CBD has antipsychotic properties, according to academic study.
Soothes Epilepsy
CBD has anti-seizure properties that are effective in treating drug-resistant forms of neurological diseases such as epilepsy. A study published in the New England Journal of Medicine found that those who took placebos had a 23% reduction in seizurefrequency when compared to those who did not.
In June 2018, the US Food and Drug Administration (FDA) gave its stamp of approval to Epidiolex, a purified form of CBD for treating two severe and rare forms of epilepsy: Dravet Syndrome (DS) and Gestaut Syndrome (LGS), which do not respond to anti-seizure medications.
Epidiolex is a pharmaceutical drug that reduces or eliminates seizures. On June 25, the medication was given the green light to be used to treat epileptic seizures caused by these sorts of epilepsy. CBD also has potential as an anti-convulsant, according to researchers, as it can assist with complications associated with epilepsy, such as neuronal injury, neurodegeneration, and mental illness.
Summary: Effective – CBD has been shown in academic studies to help reduce the severity of epileptic seizures.
Reduces PTSD Symptoms
A retrospective case series published in the Journal of Alternative and Complementary Medicine[90] has shown that combining CBD with a standard psychiatric care is associated with lower PTSD rates.
People suffering from post-traumatic stress disorder (PTSD) might be given opioids. However, because opiates can be highly addicting and put patients at risk of developing opioid use disorders later, they should not be used to treat these conditions. CBD, thankfully, provides safer treatment alternatives for people with PTSD without the negative effects.
CBD has been found to drastically reduce or even cure flashbacks, long-lasting unpleasant memories, and nightmares in people who have experienced trauma. As a result, CBD may help decrease the most serious symptoms of PTSD such as anxiety, traumatic memory recall, and restful sleep.
Summary: Effective – CBD has been shown in studies to help with post-traumatic stress disorder (PTSD) symptoms.
Digestive system
Doctors have started recommending CBD oil as a substitute therapy for patients since it was given and legalized by the FDA. Gut health and digestion are critical to one’s general well-being. The gut, among other things, is home to bacteria, parasites, and a variety of other microorganisms.
Cannabinoids can reduce inflammation, which is useful for gut health. CBD has been recommended and used to treat a variety of gastrointestinal diseases. Cannabinoid receptors aid in the control of digestive functions like saliva production, hunger, and fullness.
CBD has also been found to help with stomach bloating and swelling. CBD may be used to treat constipation, diarrhea, and abdominal discomfort in humans. CBD can also aid in the management of severe illnesses such as Crohn’s disease, IBS, and Colitis.
Summary: Partly Effective – CBD has been shown to be a digestive help in various studies.
Immunomodulating effect
The endocannabinoid system’s therapeutic use affects the immune system. Immune-cannabinoid modulation is a term used to describe this process. The ECS manages and tunes the tone, features, and overall operation of the immune system.
Although immunomodulatory effects have not been fully demonstrated, certain cannabinoids inhibit inflammatory responses in people with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, encephalomyelitis, lupus, and Parkinson’s disease at the right dosage. CBD is especially effective in this respect.
CBD is anti-inflammatory and immunosuppressive, according to studies on immune responses and inflammation. CBD’s anti-inflammatory qualities help to strengthen the immune system by reducing inflammation, which helps avoid illness.
Summary: Partly Effective – CBD has immunomodulatory properties, according to certain academic studies.
Potential Treatment for HIV-1 Infection
The failure of the immune system to function correctly is one of the causes of HIV/AIDS. HIV compromises the body’s ability to fight the virus by impairing the immune system. Because CBD can improve immunity, it may be a good choice for relieving HIV symptoms.
In 2015, researchers discovered that individuals who took CBD had more CD4 immune cells and lower viral loads when compared to typical patients. In 2003, it was reported that CBD improved T-cell counts.
T cells are critical to the immune system’s function and assist in the destruction of disease-causing germs. CBD has been found in recent studies to inhibit the activity of plasmacytoid dendritic cells, which help HIV progress into AIDS by impairing their function.
Summary: Partly Effective – CBD has been shown in studies to be able to cure HIV-1 infection.
FAQ
Is it possible to get too much CBD oil?
Because humans have such a high tolerance to CBD, it would be tough to overdose. The lethal dose in one research was estimated at around 20,000 milligrams consumed all at once.
What is the minimum age for purchasing CBD oil?
CBD is legal in all 50 states, but its legality and the legal age to purchase it differ from state to state. You must be 18 or 21 years old in many parts of the country to buy CBD oil, depending on the form of the product, how it was obtained (via hemp or marijuana), and its intended use (medical or recreational). To discover out what’s legal in your region, check your local legislation.